Gene Combination List – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genes/PINK1/genecombinations/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": [
        {
            "type": "GeneCombination",
            "id": "96",
            "attributes": {
                "gene_relationship": [
                    "Directly interacting",
                    "Involved in the same disease",
                    "Relevant pathways for phenotype",
                    "Same pathway",
                    "Same organelle"
                ],
                "protein_interactions": [
                    "(PINK1, PRKN)"
                ],
                "common_pathways": [
                    "Selective autophagy",
                    "PINK1-PRKN Mediated Mitophagy",
                    "Pathways of neurodegeneration - multiple diseases",
                    "Mitophagy",
                    "Amyotrophic lateral sclerosis",
                    "Macroautophagy",
                    "Autophagy"
                ],
                "genecomb_metascore": 3,
                "lastmodified": "2021-10-18T11:00:49.478480"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 6
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI128"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI129"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI127"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI228"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI229"
                        },
                        {
                            "type": "Combination",
                            "id": "OLI230"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/96/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/96/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PINK1"
                        },
                        {
                            "type": "Gene",
                            "id": "PRKN"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/96/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/96/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/96/?format=api"
            }
        },
        {
            "type": "GeneCombination",
            "id": "137",
            "attributes": {
                "gene_relationship": [
                    "Involved in the same disease",
                    "Directly interacting",
                    "Same pathway",
                    "Relevant pathways for phenotype"
                ],
                "protein_interactions": [
                    "(PARK7, PINK1)"
                ],
                "common_pathways": [
                    "Macroautophagy",
                    "Pathways of neurodegeneration - multiple diseases",
                    "Selective autophagy",
                    "Autophagy"
                ],
                "genecomb_metascore": 3,
                "lastmodified": "2021-10-18T11:00:51.942744"
            },
            "relationships": {
                "combination_set": {
                    "meta": {
                        "count": 1
                    },
                    "data": [
                        {
                            "type": "Combination",
                            "id": "OLI209"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/137/relationships/combination_set?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/137/combinations/?format=api"
                    }
                },
                "genes": {
                    "meta": {
                        "count": 2
                    },
                    "data": [
                        {
                            "type": "Gene",
                            "id": "PARK7"
                        },
                        {
                            "type": "Gene",
                            "id": "PINK1"
                        }
                    ],
                    "links": {
                        "self": "https://olida.ibsquare.be/api/genecombinations/137/relationships/genes?format=api",
                        "related": "https://olida.ibsquare.be/api/genecombinations/137/genes/?format=api"
                    }
                }
            },
            "links": {
                "self": "https://olida.ibsquare.be/api/genecombinations/137/?format=api"
            }
        }
    ]
}