Gene Combination Instance – Django REST framework

This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.

GET /api/genecombinations/1278/?format=api

HTTP 200 OK
Allow: GET, HEAD, OPTIONS
Content-Type: application/vnd.api+json
Vary: Accept

{
    "data": {
        "type": "GeneCombination",
        "id": "1278",
        "attributes": {
            "gene_relationship": [
                "Affecting the same tissue",
                "Directly interacting",
                "Similar function",
                "Relevant pathways for phenotype",
                "Involved in the same disease"
            ],
            "protein_interactions": [
                "(MYH9, MYO5A)"
            ],
            "common_pathways": [
                "Infectious disease",
                "Leishmania phagocytosis",
                "Leishmania infection",
                "Membrane Trafficking",
                "Immune System",
                "Innate Immune System",
                "Vesicle-mediated transport",
                "FCGR3A-mediated phagocytosis",
                "Fcgamma receptor (FCGR) dependent phagocytosis",
                "Regulation of actin dynamics for phagocytic cup formation",
                "Parasite infection",
                "Translocation of SLC2A4 (GLUT4) to the plasma membrane",
                "Disease",
                "Pathogenic Escherichia coli infection"
            ],
            "genecomb_metascore": 2,
            "lastmodified": "2024-03-01T14:30:56.122956"
        },
        "relationships": {
            "combination_set": {
                "meta": {
                    "count": 1
                },
                "data": [
                    {
                        "type": "Combination",
                        "id": "OLI1803"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/1278/relationships/combination_set?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/1278/combinations/?format=api"
                }
            },
            "genes": {
                "meta": {
                    "count": 2
                },
                "data": [
                    {
                        "type": "Gene",
                        "id": "MYH9"
                    },
                    {
                        "type": "Gene",
                        "id": "MYO5A"
                    }
                ],
                "links": {
                    "self": "https://olida.ibsquare.be/api/genecombinations/1278/relationships/genes?format=api",
                    "related": "https://olida.ibsquare.be/api/genecombinations/1278/genes/?format=api"
                }
            }
        },
        "links": {
            "self": "https://olida.ibsquare.be/api/genecombinations/1278/?format=api"
        }
    }
}