Gene List
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/genecombinations/1067/genes/?format=api
{ "data": [ { "type": "Gene", "id": "CTU2", "attributes": { "go_molecular_function": [ "['sulfurtransferase activity', 'tRNA binding', 'nucleotidyltransferase activity', 'protein binding']" ], "pathway_id": [ "kegg_path:hsa04122", "R-HSA-6782315", "R-HSA-72306", "R-HSA-8953854" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q2VPK5", "ensembl_id": "None", "entrez_id": "ENSG00000174177", "chromosome_number": "16", "lastmodified": "2023-05-16T12:02:33.504062" }, "relationships": { "variant_set": { "meta": { "count": 3 }, "data": [ { "type": "SmallVariant", "id": "3162" }, { "type": "SmallVariant", "id": "3195" }, { "type": "SmallVariant", "id": "3322" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CTU2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CTU2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 3 }, "data": [ { "type": "GeneCombination", "id": "1055" }, { "type": "GeneCombination", "id": "1067" }, { "type": "GeneCombination", "id": "1118" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/CTU2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/CTU2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/CTU2/?format=api" } }, { "type": "Gene", "id": "FLRT3", "attributes": { "go_molecular_function": [ "['protein homodimerization activity', 'protein-macromolecule adaptor activity', 'protein binding', 'fibroblast growth factor receptor binding', 'chemorepellent activity']" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-162582", "R-HSA-190236", "R-HSA-376176", "R-HSA-422475", "R-HSA-5654687", "R-HSA-5654736", "R-HSA-9006934", "R-HSA-9675108" ], "essential_gene": "Essential", "status": "CU", "uniprot_acc": "Q9NZU0", "ensembl_id": "None", "entrez_id": "ENSG00000125848", "chromosome_number": "20", "lastmodified": "2021-10-18T11:00:44.905326" }, "relationships": { "variant_set": { "meta": { "count": 11 }, "data": [ { "type": "SmallVariant", "id": "805" }, { "type": "SmallVariant", "id": "806" }, { "type": "SmallVariant", "id": "815" }, { "type": "SmallVariant", "id": "2682" }, { "type": "SmallVariant", "id": "2695" }, { "type": "SmallVariant", "id": "2730" }, { "type": "SmallVariant", "id": "3194" }, { "type": "SmallVariant", "id": "3225" }, { "type": "SmallVariant", "id": "3234" }, { "type": "SmallVariant", "id": "3258" }, { "type": "SmallVariant", "id": "3474" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLRT3/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLRT3/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 9 }, "data": [ { "type": "GeneCombination", "id": "252" }, { "type": "GeneCombination", "id": "256" }, { "type": "GeneCombination", "id": "897" }, { "type": "GeneCombination", "id": "909" }, { "type": "GeneCombination", "id": "1067" }, { "type": "GeneCombination", "id": "1079" }, { "type": "GeneCombination", "id": "1082" }, { "type": "GeneCombination", "id": "1094" }, { "type": "GeneCombination", "id": "1166" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/FLRT3/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/FLRT3/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/FLRT3/?format=api" } }, { "type": "Gene", "id": "MAMLD1", "attributes": { "go_molecular_function": [ "['molecular_function']" ], "pathway_id": [ "R-HSA-1266738", "R-HSA-157118", "R-HSA-162582", "R-HSA-1643685", "R-HSA-186712", "R-HSA-1912408", "R-HSA-1912422", "R-HSA-1980143", "R-HSA-1980145", "R-HSA-210744", "R-HSA-2122947", "R-HSA-212436", "R-HSA-2197563", "R-HSA-2644602", "R-HSA-2644603", "R-HSA-2644606", "R-HSA-2894858", "R-HSA-2894862", "R-HSA-350054", "R-HSA-5663202", "R-HSA-73857", "R-HSA-74160", "R-HSA-8878159", "R-HSA-8941856", "R-HSA-9012852", "R-HSA-9013508", "R-HSA-9013694", "R-HSA-9013695", "R-HSA-1266738", "R-HSA-157118", "R-HSA-162582", "R-HSA-1643685", "R-HSA-186712", "R-HSA-1912408", "R-HSA-1912422", "R-HSA-1980143", "R-HSA-1980145", "R-HSA-210744", "R-HSA-2122947", "R-HSA-212436", "R-HSA-2197563", "R-HSA-2644602", "R-HSA-2644603", "R-HSA-2644606", "R-HSA-2894858", "R-HSA-2894862", "R-HSA-350054", "R-HSA-5663202", "R-HSA-73857", "R-HSA-74160", "R-HSA-8878159", "R-HSA-8941856", "R-HSA-9012852", "R-HSA-9013508", "R-HSA-9013694", "R-HSA-9013695" ], "essential_gene": null, "status": "CU", "uniprot_acc": "Q13495", "ensembl_id": "None", "entrez_id": "ENSG00000013619", "chromosome_number": "X", "lastmodified": "2021-10-18T11:00:44.997839" }, "relationships": { "variant_set": { "meta": { "count": 22 }, "data": [ { "type": "SmallVariant", "id": "581" }, { "type": "SmallVariant", "id": "717" }, { "type": "SmallVariant", "id": "722" }, { "type": "SmallVariant", "id": "729" }, { "type": "SmallVariant", "id": "733" }, { "type": "SmallVariant", "id": "736" }, { "type": "SmallVariant", "id": "742" }, { "type": "SmallVariant", "id": "745" }, { "type": "SmallVariant", "id": "752" }, { "type": "SmallVariant", "id": "757" }, { "type": "SmallVariant", "id": "1268" }, { "type": "SmallVariant", "id": "1278" }, { "type": "SmallVariant", "id": "1280" }, { "type": "SmallVariant", "id": "1283" }, { "type": "SmallVariant", "id": "1294" }, { "type": "SmallVariant", "id": "1310" }, { "type": "SmallVariant", "id": "1316" }, { "type": "SmallVariant", "id": "3192" }, { "type": "SmallVariant", "id": "3200" }, { "type": "SmallVariant", "id": "3252" }, { "type": "SmallVariant", "id": "3259" }, { "type": "SmallVariant", "id": "3325" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAMLD1/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAMLD1/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 26 }, "data": [ { "type": "GeneCombination", "id": "236" }, { "type": "GeneCombination", "id": "240" }, { "type": "GeneCombination", "id": "200" }, { "type": "GeneCombination", "id": "237" }, { "type": "GeneCombination", "id": "238" }, { "type": "GeneCombination", "id": "231" }, { "type": "GeneCombination", "id": "232" }, { "type": "GeneCombination", "id": "233" }, { "type": "GeneCombination", "id": "234" }, { "type": "GeneCombination", "id": "235" }, { "type": "GeneCombination", "id": "239" }, { "type": "GeneCombination", "id": "406" }, { "type": "GeneCombination", "id": "407" }, { "type": "GeneCombination", "id": "408" }, { "type": "GeneCombination", "id": "405" }, { "type": "GeneCombination", "id": "409" }, { "type": "GeneCombination", "id": "410" }, { "type": "GeneCombination", "id": "411" }, { "type": "GeneCombination", "id": "412" }, { "type": "GeneCombination", "id": "1067" }, { "type": "GeneCombination", "id": "1068" }, { "type": "GeneCombination", "id": "1091" }, { "type": "GeneCombination", "id": "1092" }, { "type": "GeneCombination", "id": "1095" }, { "type": "GeneCombination", "id": "1120" }, { "type": "GeneCombination", "id": "1122" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MAMLD1/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MAMLD1/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MAMLD1/?format=api" } }, { "type": "Gene", "id": "RXFP2", "attributes": { "go_molecular_function": [ "['G protein-coupled peptide receptor activity', 'protein-hormone receptor activity']" ], "pathway_id": [ "kegg_path:hsa04080", "kegg_path:hsa04926", "R-HSA-162582", "R-HSA-1643685", "R-HSA-372790", "R-HSA-373076", "R-HSA-375276", "R-HSA-388396", "R-HSA-418555", "R-HSA-444821", "R-HSA-500792", "R-HSA-5663205", "R-HSA-9658195", "R-HSA-9660821", "R-HSA-9662851", "R-HSA-9664433" ], "essential_gene": "Non-essential", "status": "CU", "uniprot_acc": "Q8WXD0", "ensembl_id": "None", "entrez_id": "ENSG00000133105", "chromosome_number": "13", "lastmodified": "2023-05-16T12:02:33.575225" }, "relationships": { "variant_set": { "meta": { "count": 4 }, "data": [ { "type": "SmallVariant", "id": "3193" }, { "type": "SmallVariant", "id": "3251" }, { "type": "SmallVariant", "id": "3287" }, { "type": "SmallVariant", "id": "3319" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RXFP2/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RXFP2/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 6 }, "data": [ { "type": "GeneCombination", "id": "1067" }, { "type": "GeneCombination", "id": "1091" }, { "type": "GeneCombination", "id": "1092" }, { "type": "GeneCombination", "id": "1106" }, { "type": "GeneCombination", "id": "1116" }, { "type": "GeneCombination", "id": "1122" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/RXFP2/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/RXFP2/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/RXFP2/?format=api" } } ], "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "size": 4 } }