| GENE NAME | ZIC3 |
| CHROMOSOME | X |
| ENSEMBL ID | ENSG00000156925 |
| ENTREZ ID | 7547 |
| UNIPROT ACCESSION NUMBER | O60481 |
| GO MOLECULAR FUNCTION | RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding; DNA-binding transcription factor activity |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | R-HSA-2892247; R-HSA-452723; R-HSA-1266738; hsa04550 |
| 6 combinations linked to ZIC3 | OLI713; OLI149; OLI696; OLI759; OLI151; OLI722 |
| 1 variant linked to ZIC3 | ZIC3:c.49G>T, p.Gly17Cys |
| 3 diseases linked to ZIC3 | Ventricular septal defect; Isolated anencephaly; Transposition of the great arteries |