GENE NAME | ZEB1 |
CHROMOSOME | 10 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000148516 |
UNIPROT ACCESSION NUMBER | P37275 |
GO MOLECULAR FUNCTION | ['DNA-binding transcription repressor activity, RNA polymerase II-specific', 'chromatin binding', 'zinc ion binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'E-box binding', 'protein binding', 'DNA-binding transcription factor activity', 'DNA-binding transcription factor activity, RNA polymerase II-specific'] |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa05202; hsa05206; hsa05215; R-HSA-1280215; R-HSA-168256; R-HSA-449147; R-HSA-6785807 |
1 combination linked to ZEB1 | OLI1681 |
1 variant linked to ZEB1 | ZEB1:c.2184A>C, p.Glu728Asp |
1 disease linked to ZEB1 | Non-Syndromic genetic keratoconus |