Details for Gene ZEB1

GENE NAME ZEB1
CHROMOSOME 10
ENSEMBL ID None
ENTREZ ID ENSG00000148516
UNIPROT ACCESSION NUMBER P37275
GO MOLECULAR FUNCTION ['DNA-binding transcription repressor activity, RNA polymerase II-specific', 'chromatin binding', 'zinc ion binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'E-box binding', 'protein binding', 'DNA-binding transcription factor activity', 'DNA-binding transcription factor activity, RNA polymerase II-specific']
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa05202; hsa05206; hsa05215; R-HSA-1280215; R-HSA-168256; R-HSA-449147; R-HSA-6785807
1 combination linked to ZEB1 OLI1681
1 variant linked to ZEB1 ZEB1:c.2184A>C, p.Glu728Asp
1 disease linked to ZEB1 Non-Syndromic genetic keratoconus

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