GENE NAME | WT1 |
CHROMOSOME | 11 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000184937 |
UNIPROT ACCESSION NUMBER | J3KNN9 |
GO MOLECULAR FUNCTION | ['zinc ion binding', 'sequence-specific DNA binding', 'hemi-methylated DNA-binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'RNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'transcription cis-regulatory region binding', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'protein binding', 'C2H2 zinc finger domain binding', 'DNA-binding transcription factor activity', 'double-stranded methylated DNA binding'] |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa05202; R-HSA-1266738; R-HSA-9690406; hsa05202 |
1 combination linked to WT1 | OLI1509 |
1 variant linked to WT1 | WT1:c.299C>G, p.Ala100Gly |
1 disease linked to WT1 | 46,XY disorder of sex development |