GENE NAME | VEGFA |
CHROMOSOME | 6 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000112715 |
UNIPROT ACCESSION NUMBER | J3KPA4 |
GO MOLECULAR FUNCTION | ['vascular endothelial growth factor receptor 2 binding', 'extracellular matrix binding', 'fibronectin binding', 'protein homodimerization activity', 'growth factor activity', 'vascular endothelial growth factor receptor 1 binding', 'vascular endothelial growth factor receptor binding', 'protein binding', 'platelet-derived growth factor receptor binding', 'heparin binding', 'receptor ligand activity', 'chemoattractant activity', 'identical protein binding', 'cytokine activity'] |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa01521; hsa04010; hsa04014; hsa04015; hsa04020; hsa04066; hsa04151; hsa04370; hsa04510; hsa04926; hsa04933; hsa05163; hsa05165; hsa05167; hsa05200; hsa05205; hsa05206; hsa05211; hsa05212; hsa05219; hsa05323; hsa05418; R-HSA-109582; R-HSA-114608; R-HSA-1234158; R-HSA-1234174; R-HSA-1280215; R-HSA-162582; R-HSA-168256; R-HSA-194138; R-HSA-194313; R-HSA-195399; R-HSA-212436; R-HSA-2262752; R-HSA-449147; R-HSA-6785807; R-HSA-73857; R-HSA-74160; R-HSA-76002; R-HSA-76005; R-HSA-8864260; R-HSA-8866910; R-HSA-8953897; R-HSA-9006934 |
2 combinations linked to VEGFA | OLI1238; OLI1588 |
2 variants linked to VEGFA | VEGFA:c.100C>T, p.Pro34Ser; VEGFA:c.1015C>T, p.Arg339Trp |
2 diseases linked to VEGFA | Amyotrophic lateral sclerosis; Recurrent implantation failure,Primary infertility |