Details for Gene VCP

GENE NAME VCP
CHROMOSOME 9
ENSEMBL ID ENSG00000165280
ENTREZ ID 7415
UNIPROT ACCESSION NUMBER P55072
GO MOLECULAR FUNCTION protein phosphatase binding; ADP binding; K48-linked polyubiquitin modification-dependent protein binding; protein domain specific binding; protein binding; ATP hydrolysis activity; deubiquitinase activator activity; identical protein binding; polyubiquitin modification-dependent protein binding; ubiquitin-like protein ligase binding; ubiquitin protein ligase binding; lipid binding; ubiquitin-specific protease binding; ATP binding; RNA binding; MHC class I protein binding; BAT3 complex binding
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-446203; hsa04141; R-HSA-9612973; R-HSA-73893; R-HSA-5663205; R-HSA-1632852; hsa05022; R-HSA-110320; R-HSA-5358346; R-HSA-5663202; R-HSA-2262752; R-HSA-5678895; R-HSA-8953897; R-HSA-162582; R-HSA-9678110; R-HSA-5689877; R-HSA-382551; R-HSA-5688426; R-HSA-9694614; R-HSA-5619115; R-HSA-9694516; R-HSA-168249; R-HSA-392499; R-HSA-5362768; R-HSA-8852135; R-HSA-9679506; R-HSA-532668; R-HSA-1643685; R-HSA-168256; R-HSA-8866654; R-HSA-8876725; R-HSA-9678108; R-HSA-382556; R-HSA-5358351; R-HSA-73894; R-HSA-9646399; hsa05134; R-HSA-110313; R-HSA-5619084; R-HSA-5689896; R-HSA-3371511; R-HSA-6798695; R-HSA-5387390; R-HSA-3371556; R-HSA-597592; hsa05014; R-HSA-9663891
2 combinations linked to VCP OLI769; OLI956
2 variants linked to VCP VCP:p.Arg155His; VCP:c.463C>T, p.Arg155Cys
1 disease linked to VCP Amyotrophic lateral sclerosis

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