Details for Gene TYK2

GENE NAME TYK2
CHROMOSOME 19
ENSEMBL ID None
ENTREZ ID ENSG00000105397
UNIPROT ACCESSION NUMBER P29597
GO MOLECULAR FUNCTION ['non-membrane spanning protein tyrosine kinase activity', 'protein tyrosine kinase activity', 'ATP binding', 'type 1 angiotensin receptor binding', 'protein binding', 'protein serine/threonine/tyrosine kinase activity', 'growth hormone receptor binding']
ESSENTIAL IN MOUSE Non-essential
PATHWAYS hsa04217; hsa04380; hsa04621; hsa04630; hsa04658; hsa04659; hsa05145; hsa05160; hsa05161; hsa05162; hsa05164; hsa05165; hsa05167; hsa05168; hsa05169; hsa05171; hsa04217; hsa04380; hsa04621; hsa04630; hsa04658; hsa04659; hsa05145; hsa05160; hsa05161; hsa05162; hsa05164; hsa05165; hsa05167; hsa05168; hsa05169; hsa05171; R-HSA-1059683; R-HSA-110056; R-HSA-112409; R-HSA-112411; R-HSA-1280215; R-HSA-162582; R-HSA-1643685; R-HSA-168256; R-HSA-447115; R-HSA-449147; R-HSA-449836; R-HSA-5663205; R-HSA-5683057; R-HSA-5684996; R-HSA-6783589; R-HSA-6783783; R-HSA-6785807; R-HSA-6788467; R-HSA-8854691; R-HSA-8984722; R-HSA-9020591; R-HSA-9020933; R-HSA-9020956; R-HSA-909733; R-HSA-912694; R-HSA-913531; R-HSA-9679191; R-HSA-9679506
2 combinations linked to TYK2 OLI1329; OLI1332
2 variants linked to TYK2 TYK2:c.2441C>T, ; TYK2:c.157G>A,
1 disease linked to TYK2 Primary immunodeficiency
Found any issues with the data on this page? Report this entry.