| GENE NAME | TREX1 |
| CHROMOSOME | 3 |
| ENSEMBL ID | ENSG00000213689 |
| ENTREZ ID | 11277 |
| UNIPROT ACCESSION NUMBER | Q9NSU2 |
| GO MOLECULAR FUNCTION | DNA binding, bending; single-stranded DNA binding; MutSalpha complex binding; double-stranded DNA binding; exodeoxyribonuclease III activity; protein homodimerization activity; MutLalpha complex binding; metal ion binding; WW domain binding; magnesium ion binding; 3'-5' exonuclease activity; adenyl deoxyribonucleotide binding; 3'-5'-exodeoxyribonuclease activity |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | R-HSA-3134975; R-HSA-168249; R-HSA-3248023; R-HSA-168256; hsa03460; R-HSA-1834941; R-HSA-1834949; R-HSA-3270619; hsa04623 |
| 1 combination linked to TREX1 | OLI931 |
| 1 variant linked to TREX1 | TREX1:c.340C>T, p.Arg114Cys |
| 1 disease linked to TREX1 | Transposition of the great arteries |