| GENE NAME | TP63 |
| CHROMOSOME | 3 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000073282 |
| UNIPROT ACCESSION NUMBER | Q9H3D4 |
| GO MOLECULAR FUNCTION | ['chromatin binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'damaged DNA binding', 'WW domain binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'p53 binding', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'DNA binding', 'protein binding', 'metal ion binding', 'MDM2/MDM4 family protein binding', 'identical protein binding', 'DNA-binding transcription factor activity'] |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | hsa05206; hsa05206; R-HSA-109581; R-HSA-109606; R-HSA-114452; R-HSA-139915; R-HSA-212436; R-HSA-3700989; R-HSA-5357801; R-HSA-5628897; R-HSA-5633007; R-HSA-5633008; R-HSA-6803204; R-HSA-6803205; R-HSA-6803207; R-HSA-6803211; R-HSA-6804759; R-HSA-73857; R-HSA-74160 |
| 2 combinations linked to TP63 | OLI1064; OLI1243 |
| 2 variants linked to TP63 | TP63:c.1927C>T, p.Arg643Ter; TP63:c.1594C>G, p.Pro532Ala |
| 2 diseases linked to TP63 | Primary ovarian failure; Hypodontia |