| GENE NAME | TLR4 |
| CHROMOSOME | 9 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000136869 |
| UNIPROT ACCESSION NUMBER | O00206 |
| GO MOLECULAR FUNCTION | ['signaling receptor activity', 'signaling receptor binding', 'identical protein binding', 'transmembrane signaling receptor activity', 'protein heterodimerization activity', 'protein binding', 'NAD+ nucleotidase, cyclic ADP-ribose generating', 'amyloid-beta binding', 'lipopolysaccharide binding', 'lipopolysaccharide immune receptor activity', 'NAD(P)+ nucleosidase activity'] |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | hsa04064; hsa04066; hsa04145; hsa04151; hsa04217; hsa04613; hsa04620; hsa04621; hsa05130; hsa05131; hsa05132; hsa05133; hsa05134; hsa05135; hsa05140; hsa05142; hsa05144; hsa05145; hsa05146; hsa05152; hsa05161; hsa05162; hsa05164; hsa05170; hsa05171; hsa05205; hsa05235; hsa05321; hsa05323; R-HSA-109581; R-HSA-1236974; R-HSA-1236975; R-HSA-1280218; R-HSA-140534; R-HSA-1643685; R-HSA-166016; R-HSA-166058; R-HSA-166166; R-HSA-168138; R-HSA-168179; R-HSA-168181; R-HSA-168188; R-HSA-168249; R-HSA-168256; R-HSA-168898; R-HSA-181438; R-HSA-2562578; R-HSA-5260271; R-HSA-5357769; R-HSA-5357801; R-HSA-5602358; R-HSA-5602498; R-HSA-5603041; R-HSA-5686938; R-HSA-936964; R-HSA-937041; R-HSA-937061; R-HSA-937072; R-HSA-975138; R-HSA-975155; R-HSA-975163; R-HSA-983169 |
| 1 combination linked to TLR4 | OLI1697 |
| 1 variant linked to TLR4 | TLR4:c.2071C>G, p.Arg691Gly |
| 1 disease linked to TLR4 | Schizophrenia |