Details for Gene TIRAP

GENE NAME TIRAP
CHROMOSOME 11
ENSEMBL ID None
ENTREZ ID ENSG00000150455
UNIPROT ACCESSION NUMBER P58753
GO MOLECULAR FUNCTION ['protein kinase C binding', 'protein-macromolecule adaptor activity', 'Toll-like receptor 4 binding', 'Toll-like receptor 2 binding', 'protein binding', 'phosphatidylinositol-4,5-bisphosphate binding', 'NAD+ nucleosidase activity', 'identical protein binding']
ESSENTIAL IN MOUSE Non-essential
PATHWAYS hsa04064; hsa04620; hsa05130; hsa05132; hsa05133; hsa05152; hsa05161; hsa05235; hsa04064; hsa04620; hsa05130; hsa05132; hsa05133; hsa05152; hsa05161; hsa05235; R-HSA-1236974; R-HSA-1236975; R-HSA-1280218; R-HSA-1643685; R-HSA-166016; R-HSA-166058; R-HSA-168179; R-HSA-168188; R-HSA-168249; R-HSA-168256; R-HSA-168898; R-HSA-181438; R-HSA-5260271; R-HSA-5602358; R-HSA-5602498; R-HSA-5603041; R-HSA-983169
2 combinations linked to TIRAP OLI1716; OLI1717
2 variants linked to TIRAP TIRAP:p.Glu132Lys; TIRAP:p.Asp96Asn
1 disease linked to TIRAP Common variable immunodeficiency

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