GENE NAME | TIRAP |
CHROMOSOME | 11 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000150455 |
UNIPROT ACCESSION NUMBER | P58753 |
GO MOLECULAR FUNCTION | ['protein kinase C binding', 'protein-macromolecule adaptor activity', 'Toll-like receptor 4 binding', 'Toll-like receptor 2 binding', 'protein binding', 'phosphatidylinositol-4,5-bisphosphate binding', 'NAD+ nucleosidase activity', 'identical protein binding'] |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | hsa04064; hsa04620; hsa05130; hsa05132; hsa05133; hsa05152; hsa05161; hsa05235; hsa04064; hsa04620; hsa05130; hsa05132; hsa05133; hsa05152; hsa05161; hsa05235; R-HSA-1236974; R-HSA-1236975; R-HSA-1280218; R-HSA-1643685; R-HSA-166016; R-HSA-166058; R-HSA-168179; R-HSA-168188; R-HSA-168249; R-HSA-168256; R-HSA-168898; R-HSA-181438; R-HSA-5260271; R-HSA-5602358; R-HSA-5602498; R-HSA-5603041; R-HSA-983169 |
2 combinations linked to TIRAP | OLI1716; OLI1717 |
2 variants linked to TIRAP | TIRAP:p.Glu132Lys; TIRAP:p.Asp96Asn |
1 disease linked to TIRAP | Common variable immunodeficiency |