GENE NAME | TCF3 |
CHROMOSOME | 19 |
ENSEMBL ID | ENSG00000071564 |
ENTREZ ID | 6929 |
UNIPROT ACCESSION NUMBER | P15923 |
GO MOLECULAR FUNCTION | protein binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein heterodimerization activity; protein homodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | R-HSA-212436; R-HSA-8939236; R-HSA-73857; R-HSA-525793; R-HSA-1266738; hsa04550; hsa05166; R-HSA-8878171; hsa05202; R-HSA-74160 |
1 combination linked to TCF3 | OLI076 |
1 variant linked to TCF3 | TCF3:p.Thr168fsTer191 |
1 disease linked to TCF3 | Common variable immunodeficiency |