Details for Gene STAT5B

GENE NAME STAT5B
CHROMOSOME 17
ENSEMBL ID None
ENTREZ ID ENSG00000173757
UNIPROT ACCESSION NUMBER P51692
GO MOLECULAR FUNCTION ['protein homodimerization activity', 'chromatin binding', 'identical protein binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'protein binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'glucocorticoid receptor binding', 'protein dimerization activity', 'DNA-binding transcription factor activity', 'DNA-binding transcription factor activity, RNA polymerase II-specific']
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa04012; hsa04062; hsa04217; hsa04630; hsa04658; hsa04659; hsa04917; hsa04933; hsa04935; hsa05161; hsa05162; hsa05166; hsa05200; hsa05203; hsa05220; hsa05221; hsa05223; R-HSA-1170546; R-HSA-1226099; R-HSA-1266695; R-HSA-1280215; R-HSA-1433557; R-HSA-162582; R-HSA-1643685; R-HSA-168256; R-HSA-1839117; R-HSA-1839124; R-HSA-186763; R-HSA-186797; R-HSA-2586552; R-HSA-449147; R-HSA-451927; R-HSA-512988; R-HSA-5655302; R-HSA-5663202; R-HSA-8854691; R-HSA-8983432; R-HSA-8985947; R-HSA-9006335; R-HSA-9006934; R-HSA-9020558; R-HSA-9020958; R-HSA-9027283; R-HSA-9607240; R-HSA-9645135; R-HSA-9669938; R-HSA-9670439; R-HSA-9682385; R-HSA-9702518; R-HSA-9703465; R-HSA-9703648; R-HSA-982772
1 combination linked to STAT5B OLI1720
1 variant linked to STAT5B STAT5B:p.Asn642His
1 disease linked to STAT5B Common variable immunodeficiency

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