| GENE NAME | STAT1 |
| CHROMOSOME | 2 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000115415 |
| UNIPROT ACCESSION NUMBER | P42224 |
| GO MOLECULAR FUNCTION | ['tumor necrosis factor receptor binding', 'protein phosphatase 2A binding', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'double-stranded DNA binding', 'protein binding', 'histone binding', 'identical protein binding', 'DNA-binding transcription factor activity', 'transcription coactivator binding', 'ubiquitin-like protein ligase binding', 'nuclear receptor binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding', 'histone acetyltransferase binding', 'cadherin binding', 'RNA polymerase II core promoter sequence-specific DNA binding', 'protein homodimerization activity', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'enzyme binding', 'CCR5 chemokine receptor binding', 'transcription corepressor binding', 'promoter-specific chromatin binding'] |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | hsa04062; hsa04217; hsa04380; hsa04620; hsa04621; hsa04625; hsa04630; hsa04658; hsa04659; hsa04917; hsa04919; hsa04933; hsa04935; hsa05140; hsa05145; hsa05152; hsa05160; hsa05161; hsa05162; hsa05164; hsa05165; hsa05167; hsa05168; hsa05169; hsa05171; hsa05200; hsa05212; hsa05235; hsa05321; R-HSA-1059683; R-HSA-1169408; R-HSA-1169410; R-HSA-1226099; R-HSA-1280215; R-HSA-1433557; R-HSA-157118; R-HSA-162582; R-HSA-1643685; R-HSA-168256; R-HSA-1839117; R-HSA-1839124; R-HSA-186763; R-HSA-186797; R-HSA-212436; R-HSA-447115; R-HSA-449147; R-HSA-451927; R-HSA-5655302; R-HSA-5663202; R-HSA-6783589; R-HSA-6785807; R-HSA-73857; R-HSA-74160; R-HSA-8854691; R-HSA-8878166; R-HSA-8939902; R-HSA-8984722; R-HSA-8985947; R-HSA-9006934; R-HSA-9012852; R-HSA-9013508; R-HSA-9020956; R-HSA-9020958; R-HSA-913531; R-HSA-9669938; R-HSA-9670439; R-HSA-9671555; R-HSA-9673767; R-HSA-9673770; R-HSA-982772 |
| 2 combinations linked to STAT1 | OLI1334; OLI1333 |
| 2 variants linked to STAT1 | STAT1:c.541+50T>C, ; STAT1:c.373-2A>C, |
| 1 disease linked to STAT1 | Primary immunodeficiency |