| GENE NAME | SPAST |
| CHROMOSOME | 2 |
| ENSEMBL ID | ENSG00000021574 |
| ENTREZ ID | 6683 |
| UNIPROT ACCESSION NUMBER | Q9UBP0 |
| GO MOLECULAR FUNCTION | alpha-tubulin binding; protein binding; ATP hydrolysis activity; isomerase activity; beta-tubulin binding; ATP binding; microtubule-severing ATPase activity; microtubule binding; protein-containing complex binding |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | R-HSA-69278; R-HSA-68886; R-HSA-68882; R-HSA-2995410; R-HSA-1640170; R-HSA-2555396; R-HSA-9668328 |
| 2 combinations linked to SPAST | OLI1149; OLI1148 |
| 2 variants linked to SPAST | Copy Number Variant deletion on chromosome 2 of the exon5 7 in the gene SPAST; SPAST:c.1212_1216del, p.Asn405LysfsTer36 |
| 1 disease linked to SPAST | Hereditary spastic paraplegia |