GENE NAME | SPARC |
CHROMOSOME | 5 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000113140 |
UNIPROT ACCESSION NUMBER | P09486 |
GO MOLECULAR FUNCTION | ['extracellular matrix binding', 'calcium ion binding', 'protein binding', 'collagen binding', 'extracellular matrix structural constituent'] |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | R-HSA-109582; R-HSA-114608; R-HSA-1236394; R-HSA-1251985; R-HSA-1474244; R-HSA-162582; R-HSA-2173782; R-HSA-3000178; R-HSA-3000497; R-HSA-5653656; R-HSA-76002; R-HSA-76005; R-HSA-9006934 |
1 combination linked to SPARC | OLI1685 |
1 variant linked to SPARC | SPARC:c.280G>A, p.Val94Met |
1 disease linked to SPARC | Non-Syndromic genetic keratoconus |