Details for Gene RIPK1

GENE NAME RIPK1
CHROMOSOME 6
ENSEMBL ID ENSG00000137275
ENTREZ ID 8737
UNIPROT ACCESSION NUMBER Q13546
GO MOLECULAR FUNCTION protein homodimerization activity; death domain binding; protein binding; JUN kinase kinase kinase activity; death receptor binding; identical protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; ubiquitin protein ligase binding; protein kinase activity; ATP binding; protein serine kinase activity; protein-containing complex binding
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa04620; R-HSA-933543; R-HSA-140534; R-HSA-5357769; hsa05170; R-HSA-9645723; hsa05169; R-HSA-1643685; R-HSA-1810476; R-HSA-2562578; R-HSA-75893; R-HSA-168898; R-HSA-5663205; hsa05132; hsa04623; hsa04622; R-HSA-5689880; hsa05160; hsa05163; R-HSA-9693928; hsa05130; R-HSA-162582; R-HSA-166166; R-HSA-5357801; R-HSA-983712; hsa04621; R-HSA-3295583; R-HSA-5357905; hsa05131; R-HSA-166016; R-HSA-168164; R-HSA-1834949; R-HSA-73887; hsa04620; hsa04668; hsa04210; hsa05170; R-HSA-168928; R-HSA-69416; R-HSA-5218859; R-HSA-5688426; R-HSA-937041; hsa04217; R-HSA-168256; R-HSA-5218900; R-HSA-9679191; R-HSA-9679506; hsa05169; R-HSA-392499; hsa04064; hsa04623; R-HSA-3371378; hsa05132; hsa05160; hsa05163; hsa04622; R-HSA-5689896; R-HSA-9686347; hsa04621; hsa05130; R-HSA-109581; R-HSA-5357786; hsa05131; R-HSA-1606322; R-HSA-5213460; R-HSA-597592; R-HSA-9013957; hsa04668; R-HSA-382551; hsa04210; R-HSA-168927; R-HSA-5357956; R-HSA-937061; R-HSA-2672351; hsa04217; hsa04064; R-HSA-168249; R-HSA-5675482
1 combination linked to RIPK1 OLI1049
1 variant linked to RIPK1 RIPK1:c.700G>A, p.Glu234Lys
1 disease linked to RIPK1 Primary ovarian failure
Found any issues with the data on this page? Report this entry.