GENE NAME | POLQ |
CHROMOSOME | 3 |
ENSEMBL ID | ENSG00000051341 |
ENTREZ ID | 10721 |
UNIPROT ACCESSION NUMBER | O75417 |
GO MOLECULAR FUNCTION | transferase activity; ATP binding; nucleotide binding; damaged DNA binding; nucleotidyltransferase activity; DNA-directed DNA polymerase activity |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | R-HSA-5693532; R-HSA-73894; R-HSA-5685939; R-HSA-5693538 |
1 combination linked to POLQ | OLI284 |
1 variant linked to POLQ | POLQ:c.6743A>G, p.Asn2248Ser |
1 disease linked to POLQ | Familial adenomatous polyposis |