GENE NAME | PLA2G6 |
CHROMOSOME | 22 |
ENSEMBL ID | ENSG00000184381 |
ENTREZ ID | 8398 |
UNIPROT ACCESSION NUMBER | O60733 |
GO MOLECULAR FUNCTION | palmitoyl-CoA hydrolase activity; lysophospholipase activity; hydrolase activity; 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent phospholipase A2 activity; calmodulin binding |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | R-HSA-8856688; R-HSA-168249; hsa00591; hsa04270; R-HSA-1483257; hsa00565; R-HSA-1482798; R-HSA-6811436; R-HSA-168256; R-HSA-1483206; R-HSA-1430728; hsa00592; R-HSA-1482788; hsa00590; R-HSA-199991; hsa00564; hsa01100; R-HSA-2029480; R-HSA-556833; hsa04014; hsa04666; R-HSA-5653656; R-HSA-6811442; R-HSA-2029485; hsa04750; R-HSA-1482839 |
1 combination linked to PLA2G6 | OLI462 |
1 variant linked to PLA2G6 | Copy Number Variant duplication on chromosome 22 of the exon14 in the gene PLA2G6 |
1 disease linked to PLA2G6 | Mitochondrial membrane protein-associated neurodegeneration |