| GENE NAME | PDE1B |
| CHROMOSOME | 12 |
| ENSEMBL ID | ENSG00000123360 |
| ENTREZ ID | 5153 |
| UNIPROT ACCESSION NUMBER | Q01064 |
| GO MOLECULAR FUNCTION | protein binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; cyclic-nucleotide phosphodiesterase activity; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | hsa04020; R-HSA-111885; hsa04740; hsa05032; R-HSA-418555; R-HSA-111997; R-HSA-392154; hsa04924; R-HSA-111996; R-HSA-418346; R-HSA-418457; hsa00230; R-HSA-111933; R-HSA-418594; hsa04924; hsa00230; hsa04020; hsa04740; R-HSA-162582; R-HSA-372790; R-HSA-9006925; hsa05032; hsa01100; R-HSA-109582; hsa04742; R-HSA-388396; hsa01100; hsa04742; R-HSA-111957; R-HSA-1489509; R-HSA-112040; R-HSA-112043 |
| 1 combination linked to PDE1B | OLI646 |
| 1 variant linked to PDE1B | PDE1B:c.47C>G, p.Ala16Gly |
| 1 disease linked to PDE1B | Schizophrenia |