Details for Gene MYC

GENE NAME MYC
CHROMOSOME 8
ENSEMBL ID ENSG00000136997
ENTREZ ID 4609
UNIPROT ACCESSION NUMBER P01106
GO MOLECULAR FUNCTION protein binding; DNA-binding transcription activator activity, RNA polymerase II-specific; core promoter sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; E-box binding; DNA-binding transcription factor activity, RNA polymerase II-specific
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-74160; R-HSA-9006936; R-HSA-1538133; hsa05216; hsa04010; hsa05213; hsa04630; hsa05160; R-HSA-5689880; hsa05132; R-HSA-2122947; hsa05205; R-HSA-9006931; hsa04151; hsa05169; R-HSA-1643685; R-HSA-453279; hsa04919; R-HSA-201681; hsa05220; R-HSA-69202; hsa04012; hsa04390; hsa05167; R-HSA-2644603; R-HSA-2894858; R-HSA-2173793; R-HSA-1280215; R-HSA-157118; R-HSA-170834; hsa05161; R-HSA-201722; hsa05210; R-HSA-4411364; R-HSA-449147; R-HSA-597592; hsa05219; R-HSA-8864260; R-HSA-8878159; hsa05221; hsa04310; R-HSA-195721; R-HSA-6785807; R-HSA-1980143; R-HSA-69206; hsa05222; R-HSA-1362277; hsa04550; R-HSA-8951430; R-HSA-1640170; R-HSA-2173796; R-HSA-212436; R-HSA-5683057; hsa05202; R-HSA-392499; hsa05225; R-HSA-2644602; R-HSA-8939211; hsa05206; hsa05230; R-HSA-168256; R-HSA-69656; R-HSA-69278; hsa04350; hsa05226; R-HSA-2644606; R-HSA-69242; R-HSA-73857; R-HSA-5688426; hsa05224; R-HSA-2894862; R-HSA-5663202; hsa05200; R-HSA-162582; R-HSA-5687128; R-HSA-9616222; hsa05163; R-HSA-1266738; R-HSA-8866911; hsa05166; hsa04218; hsa04110; R-HSA-9018519
1 combination linked to MYC OLI513
1 variant linked to MYC MYC:c.921C>G, p.His307Gln
1 disease linked to MYC MODY
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