| GENE NAME | MUTYH |
| CHROMOSOME | 1 |
| ENSEMBL ID | ENSG00000132781 |
| ENTREZ ID | 4595 |
| UNIPROT ACCESSION NUMBER | Q9UIF7 |
| GO MOLECULAR FUNCTION | MutLbeta complex binding; MutSalpha complex binding; protein binding; 4 iron, 4 sulfur cluster binding; oxidized purine DNA binding; adenine/guanine mispair binding; MutSbeta complex binding; purine-specific mismatch base pair DNA N-glycosylase activity; hydrolase activity, acting on glycosyl bonds; catalytic activity; hydrolase activity; 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity; DNA binding; MutLalpha complex binding |
| ESSENTIAL IN MOUSE | None |
| PATHWAYS | hsa03410; hsa03410 |
| 2 combinations linked to MUTYH | OLI188; OLI024 |
| 2 variants linked to MUTYH | MUTYH:c.536A>G, p.Tyr179Cys; MUTYH:c.667A>G, p.Ile223Val |
| 2 diseases linked to MUTYH | Lynch syndrome; Colorectal cancer |