GENE NAME | MMP14 |
CHROMOSOME | 14 |
ENSEMBL ID | ENSG00000157227 |
ENTREZ ID | 4323 |
UNIPROT ACCESSION NUMBER | P50281 |
GO MOLECULAR FUNCTION | protein binding; endopeptidase activity; serine-type endopeptidase activity; integrin binding; metalloaminopeptidase activity; zinc ion binding; metalloendopeptidase activity |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | R-HSA-1442490; R-HSA-1474228; hsa04668; R-HSA-1474244; hsa04928; R-HSA-1592389; hsa04912 |
1 combination linked to MMP14 | OLI1142 |
1 variant linked to MMP14 | MMP14:c.1237G>A, p.Asp413Asn |
1 disease linked to MMP14 | Mayer-Rokitansky-Küster-Hauser syndrome |