GENE NAME | MCM2 |
CHROMOSOME | 3 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000073111 |
UNIPROT ACCESSION NUMBER | P49736 |
GO MOLECULAR FUNCTION | ['single-stranded DNA binding', 'ATP hydrolysis activity', 'enzyme binding', "3'-5' DNA helicase activity", 'ATP binding', 'single-stranded DNA helicase activity', 'DNA binding', 'DNA replication origin binding', 'protein binding', 'metal ion binding', 'histone binding'] |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa03030; hsa04110; R-HSA-1640170; R-HSA-176187; R-HSA-176974; R-HSA-453279; R-HSA-68867; R-HSA-68949; R-HSA-68962; R-HSA-69002; R-HSA-69052; R-HSA-69190; R-HSA-69206; R-HSA-69239; R-HSA-69242; R-HSA-69278; R-HSA-69306; R-HSA-69481; R-HSA-69620 |
1 combination linked to MCM2 | OLI1240 |
1 variant linked to MCM2 | MCM2:c.1670C>G, p.Thr557Arg |
1 disease linked to MCM2 | Recurrent Pregnancy Loss |