Details for Gene MCM2

GENE NAME MCM2
CHROMOSOME 3
ENSEMBL ID None
ENTREZ ID ENSG00000073111
UNIPROT ACCESSION NUMBER P49736
GO MOLECULAR FUNCTION ['single-stranded DNA binding', 'ATP hydrolysis activity', 'enzyme binding', "3'-5' DNA helicase activity", 'ATP binding', 'single-stranded DNA helicase activity', 'DNA binding', 'DNA replication origin binding', 'protein binding', 'metal ion binding', 'histone binding']
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa03030; hsa04110; R-HSA-1640170; R-HSA-176187; R-HSA-176974; R-HSA-453279; R-HSA-68867; R-HSA-68949; R-HSA-68962; R-HSA-69002; R-HSA-69052; R-HSA-69190; R-HSA-69206; R-HSA-69239; R-HSA-69242; R-HSA-69278; R-HSA-69306; R-HSA-69481; R-HSA-69620
1 combination linked to MCM2 OLI1240
1 variant linked to MCM2 MCM2:c.1670C>G, p.Thr557Arg
1 disease linked to MCM2 Recurrent Pregnancy Loss

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