GENE NAME | LIG4 |
CHROMOSOME | 13 |
ENSEMBL ID | ENSG00000174405 |
ENTREZ ID | 3981 |
UNIPROT ACCESSION NUMBER | P49917 |
GO MOLECULAR FUNCTION | protein binding; protein C-terminus binding; DNA binding; DNA ligase activity; metal ion binding; DNA ligase (ATP) activity; ATP binding; ligase activity |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | R-HSA-73894; hsa03450; hsa03450; R-HSA-5693532; R-HSA-164843; R-HSA-162906; R-HSA-1643685; R-HSA-5693571; R-HSA-162587; R-HSA-162594; R-HSA-5663205; R-HSA-162592 |
1 combination linked to LIG4 | OLI927 |
1 variant linked to LIG4 | LIG4:c.833G>T, p.Val204Ile |
1 disease linked to LIG4 | Transposition of the great arteries |