Details for Gene LIG4

GENE NAME LIG4
CHROMOSOME 13
ENSEMBL ID ENSG00000174405
ENTREZ ID 3981
UNIPROT ACCESSION NUMBER P49917
GO MOLECULAR FUNCTION protein binding; protein C-terminus binding; DNA binding; DNA ligase activity; metal ion binding; DNA ligase (ATP) activity; ATP binding; ligase activity
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-73894; hsa03450; hsa03450; R-HSA-5693532; R-HSA-164843; R-HSA-162906; R-HSA-1643685; R-HSA-5693571; R-HSA-162587; R-HSA-162594; R-HSA-5663205; R-HSA-162592
1 combination linked to LIG4 OLI927
1 variant linked to LIG4 LIG4:c.833G>T, p.Val204Ile
1 disease linked to LIG4 Transposition of the great arteries

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