Details for Gene LHX3

GENE NAME LHX3
CHROMOSOME 9
ENSEMBL ID None
ENTREZ ID ENSG00000107187
UNIPROT ACCESSION NUMBER Q9UBR4
GO MOLECULAR FUNCTION ['sequence-specific DNA binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'metal ion binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding']
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-1266738; R-HSA-376176; R-HSA-422475; R-HSA-9010553; R-HSA-9675108
1 combination linked to LHX3 OLI1572
1 variant linked to LHX3 LHX3:c.221G>A, p.Cys74Tyr
1 disease linked to LHX3 Syndrome with 46,XY disorder of sex development

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