GENE NAME | LHX3 |
CHROMOSOME | 9 |
ENSEMBL ID | None |
ENTREZ ID | ENSG00000107187 |
UNIPROT ACCESSION NUMBER | Q9UBR4 |
GO MOLECULAR FUNCTION | ['sequence-specific DNA binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'RNA polymerase II-specific DNA-binding transcription factor binding', 'metal ion binding', 'RNA polymerase II transcription regulatory region sequence-specific DNA binding'] |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | R-HSA-1266738; R-HSA-376176; R-HSA-422475; R-HSA-9010553; R-HSA-9675108 |
1 combination linked to LHX3 | OLI1572 |
1 variant linked to LHX3 | LHX3:c.221G>A, p.Cys74Tyr |
1 disease linked to LHX3 | Syndrome with 46,XY disorder of sex development |