| GENE NAME | IL12B |
| CHROMOSOME | 5 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000113302 |
| UNIPROT ACCESSION NUMBER | P29460 |
| GO MOLECULAR FUNCTION | ['interleukin-12 alpha subunit binding', 'cytokine binding', 'growth factor activity', 'protein-containing complex binding', 'protein heterodimerization activity', 'protein binding', 'interleukin-23 receptor binding', 'interleukin-12 receptor binding', 'cytokine receptor activity', 'identical protein binding', 'cytokine activity'] |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | hsa04060; hsa04620; hsa04622; hsa04625; hsa04630; hsa04658; hsa04940; hsa05133; hsa05134; hsa05140; hsa05142; hsa05143; hsa05145; hsa05146; hsa05152; hsa05162; hsa05164; hsa05168; hsa05171; hsa05200; hsa05205; hsa05321; hsa05330; R-HSA-1280215; R-HSA-168256; R-HSA-447115; R-HSA-449147; R-HSA-6783783; R-HSA-6785807; R-HSA-9020591; R-HSA-9020933 |
| 1 combination linked to IL12B | OLI1332 |
| 2 variants linked to IL12B | IL12B:c.877A>G, ; IL12B:c.89, |
| 1 disease linked to IL12B | Primary immunodeficiency |