| GENE NAME | HSF1 |
| CHROMOSOME | 8 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000185122 |
| UNIPROT ACCESSION NUMBER | Q00613 |
| GO MOLECULAR FUNCTION | ['STAT family protein binding', 'sequence-specific single stranded DNA binding', 'transcription cis-regulatory region binding', 'DNA-binding transcription factor activity, RNA polymerase II-specific', 'DNA binding', 'general transcription initiation factor binding', 'protein binding', 'identical protein binding', 'DNA-binding transcription factor activity', 'sequence-specific DNA binding', 'heat shock protein binding', 'protein heterodimerization activity', 'Hsp90 protein binding', 'chromatin DNA binding', 'sequence-specific double-stranded DNA binding', 'DNA-binding transcription repressor activity, RNA polymerase II-specific', 'translation elongation factor binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'protein kinase binding', 'protein self-association', 'RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding', 'promoter-specific chromatin binding'] |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | hsa05134; R-HSA-1632852; R-HSA-2262752; R-HSA-3371453; R-HSA-3371511; R-HSA-3371556; R-HSA-3371568; R-HSA-3371571; R-HSA-8953897; R-HSA-9612973; R-HSA-9646399; R-HSA-9663891; hsa05134; R-HSA-1632852; R-HSA-2262752; R-HSA-3371453; R-HSA-3371511; R-HSA-3371556; R-HSA-3371568; R-HSA-3371571; R-HSA-8953897; R-HSA-9612973; R-HSA-9646399; R-HSA-9663891 |
| 1 combination linked to HSF1 | OLI1232 |
| 1 variant linked to HSF1 | HSF1:c.430G>A, p.Val144Met |
| 1 disease linked to HSF1 | Recurrent Pregnancy Loss |