| GENE NAME | HDAC5 |
| CHROMOSOME | 17 |
| ENSEMBL ID | ENSG00000108840 |
| ENTREZ ID | 10014 |
| UNIPROT ACCESSION NUMBER | Q9UQL6 |
| GO MOLECULAR FUNCTION | protein deacetylase activity; protein binding; histone deacetylase activity; protein kinase C binding; transcription cis-regulatory region binding; identical protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); histone deacetylase binding; metal ion binding; DNA-binding transcription factor binding; RNA polymerase II-specific DNA-binding transcription factor binding; transcription corepressor binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | R-HSA-212436; R-HSA-2122947; hsa04371; R-HSA-6807070; hsa05203; hsa05034; hsa04613; R-HSA-162582; R-HSA-1980143; R-HSA-2644606; R-HSA-8943724; R-HSA-9006925; R-HSA-1257604; R-HSA-350054; R-HSA-5663202; R-HSA-74160; hsa05206; R-HSA-1643685; R-HSA-2644602; R-HSA-2894862; R-HSA-2644603; R-HSA-2894858; R-HSA-73857; R-HSA-157118 |
| 1 combination linked to HDAC5 | OLI1066 |
| 1 variant linked to HDAC5 | HDAC5:c.446A>G, p.Glu149Gly |
| 1 disease linked to HDAC5 | Primary ovarian failure |