Details for Gene GDNF

GENE NAME GDNF
CHROMOSOME 5
ENSEMBL ID ENSG00000168621
ENTREZ ID 2668
UNIPROT ACCESSION NUMBER P39905
GO MOLECULAR FUNCTION receptor tyrosine kinase binding; protein binding; signaling receptor binding; glial cell-derived neurotrophic factor receptor binding; chemoattractant activity involved in axon guidance; growth factor activity
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-5684996; hsa04020; R-HSA-162582; R-HSA-8853659; hsa04020; R-HSA-419037; R-HSA-5673001; R-HSA-422475; R-HSA-375165; R-HSA-5683057; R-HSA-9675108; R-HSA-1266738
2 combinations linked to GDNF OLI021; OLI575
1 variant linked to GDNF GDNF:c.277C>T, p.Arg93Trp
2 diseases linked to GDNF Disorder of sex development; Hirschsprung disease

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