GENE NAME | GDNF |
CHROMOSOME | 5 |
ENSEMBL ID | ENSG00000168621 |
ENTREZ ID | 2668 |
UNIPROT ACCESSION NUMBER | P39905 |
GO MOLECULAR FUNCTION | receptor tyrosine kinase binding; protein binding; signaling receptor binding; glial cell-derived neurotrophic factor receptor binding; chemoattractant activity involved in axon guidance; growth factor activity |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | R-HSA-5684996; hsa04020; R-HSA-162582; R-HSA-8853659; hsa04020; R-HSA-419037; R-HSA-5673001; R-HSA-422475; R-HSA-375165; R-HSA-5683057; R-HSA-9675108; R-HSA-1266738 |
2 combinations linked to GDNF | OLI021; OLI575 |
1 variant linked to GDNF | GDNF:c.277C>T, p.Arg93Trp |
2 diseases linked to GDNF | Disorder of sex development; Hirschsprung disease |