GENE NAME | FZD6 |
CHROMOSOME | 8 |
ENSEMBL ID | ENSG00000164930 |
ENTREZ ID | 8323 |
UNIPROT ACCESSION NUMBER | O60353 |
GO MOLECULAR FUNCTION | Wnt-protein binding; G protein-coupled receptor activity; protein binding; Wnt-activated receptor activity |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | R-HSA-162582; R-HSA-373080; R-HSA-5663202; hsa05205; hsa05022; hsa05200; hsa05022; hsa05205; R-HSA-5340588; hsa05200; hsa04934; hsa04310; hsa04550; hsa05165; hsa04390; hsa05010; hsa05226; R-HSA-201681; hsa04150; hsa05217; R-HSA-1643685; hsa05224; hsa05225; hsa05217; hsa04150; hsa05225; hsa05224; hsa04390; R-HSA-4086400; R-HSA-4791275; hsa05226; hsa05010; hsa04934; R-HSA-500792; R-HSA-372790; hsa04550; hsa05165; hsa04310; R-HSA-195721; hsa04916; hsa04916; R-HSA-4641263; R-HSA-3858494; R-HSA-4086398 |
3 combinations linked to FZD6 | OLI712; OLI718; OLI699 |
3 variants linked to FZD6 | FZD6:c.1531C>T, p.Arg511Cys; FZD6:c.544G>A, p.Ala182Thr; FZD6:c.1214G>A, p.Arg405Gln |
1 disease linked to FZD6 | Isolated anencephaly |