GENE NAME | FZD2 |
CHROMOSOME | 17 |
ENSEMBL ID | ENSG00000180340 |
ENTREZ ID | 2535 |
UNIPROT ACCESSION NUMBER | Q14332 |
GO MOLECULAR FUNCTION | protein binding; transmembrane signaling receptor activity; Wnt-activated receptor activity; Wnt-protein binding; G protein-coupled receptor activity |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa04916; R-HSA-372790; hsa04310; R-HSA-195721; R-HSA-500792; hsa04550; hsa05165; hsa04150; hsa04934; hsa05224; R-HSA-4608870; R-HSA-4086398; hsa04390; hsa05205; hsa05010; R-HSA-3858494; hsa05225; hsa04310; hsa05217; hsa05226; hsa04916; hsa05022; R-HSA-201681; R-HSA-4641262; R-HSA-5140745; hsa05200; R-HSA-4086400; hsa05010; hsa05205; hsa04390; hsa05224; hsa04934; hsa04150; hsa04550; hsa05165; hsa05200; hsa05022; hsa05226; R-HSA-162582; hsa05217; R-HSA-373080; hsa05225 |
1 combination linked to FZD2 | OLI706 |
1 variant linked to FZD2 | FZD2:c.121C>T, p.Pro41Ser |
1 disease linked to FZD2 | Isolated anencephaly |