Details for Gene FOXL2

GENE NAME FOXL2
CHROMOSOME 3
ENSEMBL ID None
ENTREZ ID ENSG00000183770
UNIPROT ACCESSION NUMBER None
GO MOLECULAR FUNCTION ['DNA binding', 'RNA polymerase II cis-regulatory region sequence-specific DNA binding', 'ubiquitin conjugating enzyme binding', 'sequence-specific double-stranded DNA binding', 'cysteine-type endopeptidase regulator activity involved in apoptotic process', 'protein binding', 'DNA-binding transcription activator activity, RNA polymerase II-specific', 'estrogen receptor binding', 'DNA-binding transcription factor activity', 'DNA-binding transcription factor activity, RNA polymerase II-specific']
ESSENTIAL IN MOUSE Essential
PATHWAYS R-HSA-2990846; R-HSA-3108232; R-HSA-3232118; R-HSA-392499; R-HSA-597592
6 combinations linked to FOXL2 OLI1725; OLI1729; OLI1727; OLI1726; OLI091; OLI1728
2 variants linked to FOXL2 FOXL2:c.13T>A, p.Tyr5Asn; FOXL2:c.1045C>G, p.Arg349Gly
1 disease linked to FOXL2 Primary ovarian failure

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