Details for Gene FGFR2

GENE NAME FGFR2
CHROMOSOME 10
ENSEMBL ID None
ENTREZ ID ENSG00000066468
UNIPROT ACCESSION NUMBER P21802
GO MOLECULAR FUNCTION ['protein tyrosine kinase activity', 'ATP binding', 'fibroblast growth factor binding', 'protein binding', 'heparin binding', 'protein homodimerization activity', 'protein serine/threonine/tyrosine kinase activity', 'fibroblast growth factor-activated receptor activity', 'transmembrane receptor protein tyrosine kinase activity']
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa01521; hsa04010; hsa04014; hsa04015; hsa04020; hsa04144; hsa04151; hsa04550; hsa04810; hsa05200; hsa05215; hsa05226; hsa05230; R-HSA-1226099; R-HSA-1643685; R-HSA-1839126; R-HSA-2023837; R-HSA-2033519; R-HSA-5655253; R-HSA-5663202; R-HSA-8851708; R-HSA-8853333
2 combinations linked to FGFR2 OLI1520; OLI1514
2 variants linked to FGFR2 FGFR2:c.1132A>G, p.Ile378Val; FGFR2:c.34G>A, p.Val12Met
1 disease linked to FGFR2 46,XY disorder of sex development

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