GENE NAME | ERG |
CHROMOSOME | 21 |
ENSEMBL ID | ENSG00000157554 |
ENTREZ ID | 2078 |
UNIPROT ACCESSION NUMBER | P11308 |
GO MOLECULAR FUNCTION | protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; chromatin binding; sequence-specific double-stranded DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa05202; hsa05215 |
1 combination linked to ERG | OLI979 |
1 variant linked to ERG | ERG:c.275G>A, p.Cys92Tyr |
1 disease linked to ERG | Left ventricular noncompaction |