| GENE NAME | ERBB4 |
| CHROMOSOME | 2 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000178568 |
| UNIPROT ACCESSION NUMBER | Q15303 |
| GO MOLECULAR FUNCTION | ['epidermal growth factor receptor binding', 'protein tyrosine kinase activity', 'protein homodimerization activity', 'transmembrane receptor protein tyrosine kinase activity', 'protein serine/threonine/tyrosine kinase activity', 'transcription cis-regulatory region binding', 'protein binding', 'ATP binding'] |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | hsa04010; hsa04012; hsa04020; hsa04151; hsa05014; hsa05205 |
| 8 combinations linked to ERBB4 | OLI1042; OLI907; OLI882; OLI905; OLI1639; OLI1588; OLI959; OLI867 |
| 6 variants linked to ERBB4 | ERBB4:c.1972A>T, p.Ile658Phe; ERBB4:c.2395A>G, p.Met799Val; ERBB4:c.95C>T, p.Thr32Met; ERBB4:c.3344T>A, p.Val1115Glu; ERBB4:c.3446C>A, p.Gly1149Val; ERBB4:c.1879G>A, p.Gly627Ser |
| 4 diseases linked to ERBB4 | Normosmic congenital hypogonadotropic hypogonadism; Amyotrophic lateral sclerosis; Primary ovarian failure; Kallmann syndrome |