GENE NAME | ERBB3 |
CHROMOSOME | 12 |
ENSEMBL ID | ENSG00000065361 |
ENTREZ ID | 2065 |
UNIPROT ACCESSION NUMBER | P21860 |
GO MOLECULAR FUNCTION | protein binding; transmembrane signaling receptor activity; protein tyrosine kinase activator activity; identical protein binding; neuregulin receptor activity; protein serine/threonine/tyrosine kinase activity; ubiquitin protein ligase binding; neuregulin binding; growth factor binding; ErbB-3 class receptor binding; ATP binding; protein heterodimerization activity; transmembrane receptor protein tyrosine kinase activity |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa01521; hsa04151; hsa05206; hsa04020; hsa04010; hsa04012; hsa05205 |
1 combination linked to ERBB3 | OLI1055 |
1 variant linked to ERBB3 | ERBB3:c.2269dupA, p.Thr757AsnfsTer70 |
1 disease linked to ERBB3 | Primary ovarian failure |