Details for Gene ERBB3

GENE NAME ERBB3
CHROMOSOME 12
ENSEMBL ID ENSG00000065361
ENTREZ ID 2065
UNIPROT ACCESSION NUMBER P21860
GO MOLECULAR FUNCTION protein binding; transmembrane signaling receptor activity; protein tyrosine kinase activator activity; identical protein binding; neuregulin receptor activity; protein serine/threonine/tyrosine kinase activity; ubiquitin protein ligase binding; neuregulin binding; growth factor binding; ErbB-3 class receptor binding; ATP binding; protein heterodimerization activity; transmembrane receptor protein tyrosine kinase activity
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa01521; hsa04151; hsa05206; hsa04020; hsa04010; hsa04012; hsa05205
1 combination linked to ERBB3 OLI1055
1 variant linked to ERBB3 ERBB3:c.2269dupA, p.Thr757AsnfsTer70
1 disease linked to ERBB3 Primary ovarian failure

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