| GENE NAME | E2F4 |
| CHROMOSOME | 16 |
| ENSEMBL ID | ENSG00000205250 |
| ENTREZ ID | 1874 |
| UNIPROT ACCESSION NUMBER | Q16254 |
| GO MOLECULAR FUNCTION | protein dimerization activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; promoter-specific chromatin binding; DNA-binding transcription factor activity; DNA binding |
| ESSENTIAL IN MOUSE | Essential |
| PATHWAYS | R-HSA-1362300; R-HSA-6804114; hsa04110; R-HSA-453279; R-HSA-69656; hsa04350; R-HSA-69278; R-HSA-69202; R-HSA-69231; R-HSA-69242; R-HSA-73857; R-HSA-1362277; R-HSA-2173793; hsa04218; R-HSA-212436; R-HSA-3700989; R-HSA-6791312; R-HSA-1640170; R-HSA-170834; R-HSA-2173796; R-HSA-74160; R-HSA-69205; R-HSA-1538133; R-HSA-9006936; R-HSA-69236; R-HSA-162582; R-HSA-69206 |
| 1 combination linked to E2F4 | OLI402 |
| 1 variant linked to E2F4 | E2F4:c.410T>C, p.Leu137Ser |
| 1 disease linked to E2F4 | Non-acquired combined pituitary hormone deficiency |