Details for Gene DVL3

GENE NAME DVL3
CHROMOSOME 3
ENSEMBL ID ENSG00000161202
ENTREZ ID 1857
UNIPROT ACCESSION NUMBER Q92997
GO MOLECULAR FUNCTION protein binding; protease binding; frizzled binding; small GTPase binding; beta-catenin binding
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa05217; hsa05225; R-HSA-1643685; R-HSA-9664420; R-HSA-201681; R-HSA-4641262; hsa05226; hsa04390; hsa05010; R-HSA-4086400; R-HSA-5663220; hsa04150; R-HSA-201688; hsa05224; hsa04916; hsa05022; R-HSA-195258; hsa05200; R-HSA-9658195; hsa04330; hsa04310; R-HSA-195721; R-HSA-162582; R-HSA-194315; hsa04934; R-HSA-9673324; hsa04550; hsa05165; R-HSA-5368598; R-HSA-3858494; R-HSA-5663205; R-HSA-4641258
2 combinations linked to DVL3 OLI508; OLI710
2 variants linked to DVL3 DVL3:c.443G>A, p.Arg148Gln; DVL3:c.1622C>T, p.Pro541Leu
1 disease linked to DVL3 Isolated anencephaly

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