GENE NAME | DVL3 |
CHROMOSOME | 3 |
ENSEMBL ID | ENSG00000161202 |
ENTREZ ID | 1857 |
UNIPROT ACCESSION NUMBER | Q92997 |
GO MOLECULAR FUNCTION | protein binding; protease binding; frizzled binding; small GTPase binding; beta-catenin binding |
ESSENTIAL IN MOUSE | Essential |
PATHWAYS | hsa05217; hsa05225; R-HSA-1643685; R-HSA-9664420; R-HSA-201681; R-HSA-4641262; hsa05226; hsa04390; hsa05010; R-HSA-4086400; R-HSA-5663220; hsa04150; R-HSA-201688; hsa05224; hsa04916; hsa05022; R-HSA-195258; hsa05200; R-HSA-9658195; hsa04330; hsa04310; R-HSA-195721; R-HSA-162582; R-HSA-194315; hsa04934; R-HSA-9673324; hsa04550; hsa05165; R-HSA-5368598; R-HSA-3858494; R-HSA-5663205; R-HSA-4641258 |
2 combinations linked to DVL3 | OLI508; OLI710 |
2 variants linked to DVL3 | DVL3:c.443G>A, p.Arg148Gln; DVL3:c.1622C>T, p.Pro541Leu |
1 disease linked to DVL3 | Isolated anencephaly |