| GENE NAME | COMT |
| CHROMOSOME | 22 |
| ENSEMBL ID | None |
| ENTREZ ID | ENSG00000093010 |
| UNIPROT ACCESSION NUMBER | P21964 |
| GO MOLECULAR FUNCTION | ['catechol O-methyltransferase activity', 'L-dopa O-methyltransferase activity', 'magnesium ion binding', 'protein binding', 'orcinol O-methyltransferase activity', 'O-methyltransferase activity', 'methyltransferase activity'] |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | hsa00140; hsa00350; hsa01100; hsa04728; R-HSA-112311; R-HSA-112315; R-HSA-112316; R-HSA-1430728; R-HSA-156580; R-HSA-156581; R-HSA-1643685; R-HSA-211859; R-HSA-379397; R-HSA-379398; R-HSA-379401; R-HSA-5663205; R-HSA-9679191; R-HSA-9679506 |
| 1 combination linked to COMT | OLI1659 |
| 1 variant linked to COMT | COMT:c.425_426insT, p.Trp143LeufsTer27 |
| 1 disease linked to COMT | Bardet-Biedl syndrome |