Details for Gene CDK4

GENE NAME CDK4
CHROMOSOME 12
ENSEMBL ID ENSG00000135446
ENTREZ ID 1019
UNIPROT ACCESSION NUMBER P11802
GO MOLECULAR FUNCTION transferase activity; kinase activity; ATP binding; nucleotide binding; protein serine/threonine kinase activity; cyclin-dependent protein serine/threonine kinase activity
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa05222; hsa05203; R-HSA-2559580; hsa04115; hsa05162; hsa05223; hsa05160; R-HSA-912446; R-HSA-69206; hsa04151; hsa05212; R-HSA-69231; R-HSA-69242; R-HSA-9006927; hsa05164; hsa05218; R-HSA-9630794; hsa05225; hsa04530; R-HSA-69278; hsa04660; hsa05160; hsa04218; hsa05165; hsa05200; R-HSA-2262752; R-HSA-9632697; R-HSA-9632700; R-HSA-9675126; hsa05222; hsa04934; hsa05214; R-HSA-8878166; R-HSA-9630750; R-HSA-9687139; hsa05203; R-HSA-74160; hsa04115; hsa05162; R-HSA-162582; R-HSA-8849470; R-HSA-9630791; R-HSA-1500620; R-HSA-2559582; R-HSA-4839726; R-HSA-69236; hsa05223; R-HSA-8953897; R-HSA-9632693; hsa05225; hsa05220; R-HSA-69202; hsa04933; hsa05167; R-HSA-9661069; hsa04530; R-HSA-3214858; hsa04660; R-HSA-8848021; hsa05212; hsa04151; hsa05169; R-HSA-1643685; R-HSA-453279; hsa04110; R-HSA-187577; hsa05224; R-HSA-2559585; R-HSA-75815; hsa05218; hsa05164; R-HSA-9630747; hsa05200; hsa05165; hsa04934; hsa05214; R-HSA-1640170; R-HSA-212436; hsa05166; hsa05163; hsa05219; R-HSA-9675132; R-HSA-9659787; hsa04218; hsa01522; hsa05169; R-HSA-73857; hsa04110; hsa05224; R-HSA-1474165; hsa04933; hsa05167; R-HSA-381340; hsa05220; R-HSA-2559583; R-HSA-69656; hsa05219; hsa05163; R-HSA-1266738; hsa05166; R-HSA-3247509; R-HSA-9616222; hsa01522
1 combination linked to CDK4 OLI513
1 variant linked to CDK4 CDK4:c.385G>A, p.Asp129Asn
1 disease linked to CDK4 MODY
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