GENE NAME | ATF3 |
CHROMOSOME | 1 |
ENSEMBL ID | ENSG00000162772 |
ENTREZ ID | 467 |
UNIPROT ACCESSION NUMBER | P18847 |
GO MOLECULAR FUNCTION | RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription cis-regulatory region binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; protein heterodimerization activity; sequence-specific double-stranded DNA binding; protein homodimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; DNA binding |
ESSENTIAL IN MOUSE | Non-essential |
PATHWAYS | R-HSA-381119; R-HSA-2262752; R-HSA-380994; R-HSA-381042; R-HSA-392499; R-HSA-9633012; R-HSA-8953897; R-HSA-9648895 |
1 combination linked to ATF3 | OLI602 |
1 variant linked to ATF3 | ATF3:c.181G>T, p.Ala61Ser |
1 disease linked to ATF3 | Disorder of sex development |