Details for Gene ARHGEF10

GENE NAME ARHGEF10
CHROMOSOME 8
ENSEMBL ID ENSG00000104728
ENTREZ ID 9639
UNIPROT ACCESSION NUMBER O15013
GO MOLECULAR FUNCTION kinesin binding; guanyl-nucleotide exchange factor activity; protein binding
ESSENTIAL IN MOUSE None
PATHWAYS R-HSA-204998; R-HSA-193704; R-HSA-162582; R-HSA-372790; R-HSA-193648; R-HSA-388396; R-HSA-73887; R-HSA-194315; R-HSA-194840; R-HSA-416482
1 combination linked to ARHGEF10 OLI331
1 variant linked to ARHGEF10 ARHGEF10:c.700C>A, p.Pro234Thr
1 disease linked to ARHGEF10 Amyotrophic lateral sclerosis

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