Details for Gene APC

GENE NAME APC
CHROMOSOME 5
ENSEMBL ID ENSG00000134982
ENTREZ ID 324
UNIPROT ACCESSION NUMBER P25054
GO MOLECULAR FUNCTION gamma-catenin binding; microtubule binding; beta-catenin binding; protein binding
ESSENTIAL IN MOUSE Essential
PATHWAYS hsa05225; hsa05206; hsa04810; hsa05217; R-HSA-392499; R-HSA-5339716; R-HSA-111465; R-HSA-4641262; R-HSA-4839744; R-HSA-4839748; hsa05226; R-HSA-5467348; R-HSA-4839743; R-HSA-4839735; hsa05010; R-HSA-5688426; R-HSA-5467333; R-HSA-3769402; hsa05224; R-HSA-5467340; R-HSA-75153; hsa05200; R-HSA-597592; R-HSA-5467337; hsa05022; hsa05210; R-HSA-5663202; hsa04310; R-HSA-109581; R-HSA-195721; R-HSA-5358747; R-HSA-162582; R-HSA-5357801; hsa05213; R-HSA-5689896; hsa04550; hsa05165; hsa04934; R-HSA-196299; R-HSA-5358752; R-HSA-5358751; R-HSA-1643685; R-HSA-5358749; R-HSA-201681; R-HSA-195253; R-HSA-4791275; hsa04390
1 combination linked to APC OLI284
1 variant linked to APC APC:c.3468_3470delAGA, p.Glu1157del
1 disease linked to APC Familial adenomatous polyposis
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