| GENE NAME | ALOX15 |
| CHROMOSOME | 17 |
| ENSEMBL ID | ENSG00000161905 |
| ENTREZ ID | 246 |
| UNIPROT ACCESSION NUMBER | P16050 |
| GO MOLECULAR FUNCTION | linoleate 13S-lipoxygenase activity; protein binding; arachidonate 15-lipoxygenase activity; arachidonate 12(S)-lipoxygenase activity; iron ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; phosphatidylinositol-4,5-bisphosphate binding |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | R-HSA-9023661; R-HSA-9025106; hsa04217; R-HSA-168256; hsa00591; hsa04216; R-HSA-8978868; R-HSA-9026286; hsa01100; R-HSA-9018681; R-HSA-2142691; R-HSA-1280215; R-HSA-9025094; R-HSA-1430728; R-HSA-9018677; R-HSA-9018896; R-HSA-6785807; R-HSA-9018678; hsa04726; R-HSA-2142770; R-HSA-9018679; R-HSA-449147; R-HSA-2142712; R-HSA-2142753; R-HSA-9018683; R-HSA-556833; hsa00590 |
| 1 combination linked to ALOX15 | OLI329 |
| 1 variant linked to ALOX15 | ALOX15:c.82G>A, p.Gly28Ser |
| 1 disease linked to ALOX15 | Amyotrophic lateral sclerosis |