| GENE NAME | ADAMTS5 |
| CHROMOSOME | 21 |
| ENSEMBL ID | ENSG00000154736 |
| ENTREZ ID | 11096 |
| UNIPROT ACCESSION NUMBER | Q9UNA0 |
| GO MOLECULAR FUNCTION | protein binding; peptidase activity; extracellular matrix binding; endopeptidase activity; integrin binding; metallopeptidase activity; heparin binding; zinc ion binding; metalloendopeptidase activity |
| ESSENTIAL IN MOUSE | Non-essential |
| PATHWAYS | R-HSA-1643685; R-HSA-3781865; R-HSA-597592; R-HSA-5173105; R-HSA-392499; R-HSA-5668914; R-HSA-5173214; R-HSA-3906995; R-HSA-1474244; R-HSA-1474228; R-HSA-5083635 |
| 1 combination linked to ADAMTS5 | OLI1046 |
| 1 variant linked to ADAMTS5 | ADAMTS5:c.1729G>A, p.Gly577Ser |
| 1 disease linked to ADAMTS5 | Primary ovarian failure |