Gene
This API endpoint handles listing (/genes) and retrieval (/genes/<ID>/) of genes that are contained in the database due to their association to
genetic variants that are involved in at least one oligogenic combination in OLIDA.
GET /api/variants/884/gene/?format=api
{ "data": { "type": "Gene", "id": "MEFV", "attributes": { "go_molecular_function": [ "['zinc ion binding', 'protein binding', 'ubiquitin protein ligase activity', 'actin binding', 'identical protein binding']" ], "pathway_id": [ "kegg_path:hsa04621", "kegg_path:hsa05135", "R-HSA-1643685", "R-HSA-168249", "R-HSA-168256", "R-HSA-168643", "R-HSA-5663205", "R-HSA-622312", "R-HSA-844456", "R-HSA-9658195", "R-HSA-9660826", "R-HSA-9664424" ], "essential_gene": "Essential", "status": null, "uniprot_acc": "O15553", "ensembl_id": "None", "entrez_id": "ENSG00000103313", "chromosome_number": "16" }, "relationships": { "variant_set": { "meta": { "count": 17 }, "data": [ { "type": "SmallVariant", "id": "884" }, { "type": "SmallVariant", "id": "54" }, { "type": "SmallVariant", "id": "882" }, { "type": "SmallVariant", "id": "886" }, { "type": "SmallVariant", "id": "2450" }, { "type": "SmallVariant", "id": "2456" }, { "type": "SmallVariant", "id": "3715" }, { "type": "SmallVariant", "id": "3717" }, { "type": "SmallVariant", "id": "3720" }, { "type": "SmallVariant", "id": "3721" }, { "type": "SmallVariant", "id": "3722" }, { "type": "SmallVariant", "id": "3723" }, { "type": "SmallVariant", "id": "3727" }, { "type": "SmallVariant", "id": "3729" }, { "type": "SmallVariant", "id": "3745" }, { "type": "SmallVariant", "id": "3746" }, { "type": "SmallVariant", "id": "3747" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MEFV/relationships/variant_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MEFV/variants/?format=api" } }, "genecombination_set": { "meta": { "count": 10 }, "data": [ { "type": "GeneCombination", "id": "22" }, { "type": "GeneCombination", "id": "274" }, { "type": "GeneCombination", "id": "275" }, { "type": "GeneCombination", "id": "826" }, { "type": "GeneCombination", "id": "829" }, { "type": "GeneCombination", "id": "1266" }, { "type": "GeneCombination", "id": "1264" }, { "type": "GeneCombination", "id": "1262" }, { "type": "GeneCombination", "id": "1261" }, { "type": "GeneCombination", "id": "1257" } ], "links": { "self": "https://olida.ibsquare.be/api/genes/MEFV/relationships/genecombination_set?format=api", "related": "https://olida.ibsquare.be/api/genes/MEFV/genecombinations/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genes/MEFV/?format=api" } }, "meta": { "database_name": "OLIgogenic diseases DAtabase (OLIDA)", "resource_url": "olida.ibsquare.be", "api_release_year": "2021", "api_developer": [ [ "Arnau Dillen", "arnau.dillen@ulb.ac.be" ], [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_version": "0.3", "api_maintainers": [ [ "Charlotte Nachtegael", "charlotte.nachtegael@ulb.be" ] ], "api_documentation": [ "olida.ibsquare.be/api/swagger", "olida.ibsquare.be/api/redoc" ], "copyright": "Copyright (c) 2025 · OLIDA All Rights Reserved.", "license": "CC Attribution-NonCommercial 4.0 International License", "ontologies": { "ORDO": "http://bioportal.bioontology.org/ontologies/ORDO", "GENO": "http://purl.obolibrary.org/obo/geno.owl", "MI": "http://purl.obolibrary.org/obo/mi.owl", "NCIT": "http://purl.obolibrary.org/obo/ncit.owl", "OGI": "http://purl.obolibrary.org/obo/ogi.owl", "OGG": "http://purl.obolibrary.org/obo/ogg.owl" }, "relevant_publications_doi": [ "10.1093/nar/gkv1068", "10.1093/database/baac023" ], "lastmodified": "2021-10-18T11:00:45.001835", "status": "CU", "curator": null, "submitter": "cnachteg" } }