Gene Combination List
This API endpoint handles listing (/references) and retrieval (/references/<ID>/) of References from the database
that support the inclusion of at least one oligogenic combination in OLIDA.
GET /api/genes/MEFV/genecombinations/?format=api
{ "data": [ { "type": "GeneCombination", "id": "22", "attributes": { "gene_relationship": [ "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:00:46.047300" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI026" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/22/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/22/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "TRAP1" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/22/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/22/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/22/?format=api" } }, { "type": "GeneCombination", "id": "274", "attributes": { "gene_relationship": [ "Involved in the same disease", "Directly interacting", "Same pathway" ], "protein_interactions": [ "(MEFV, NLRP3)" ], "common_pathways": [ "NOD-like receptor signaling pathway", "Infectious disease", "Cell recruitment (pro-inflammatory response)", "Disease", "Immune System", "Leishmania infection", "The NLRP3 inflammasome", "Inflammasomes", "leucine rich repeat containing receptor (NLR) signaling pathways", "Nucleotide-binding domain", "Purinergic signaling in leishmaniasis infection", "Innate Immune System" ], "genecomb_metascore": 2, "lastmodified": "2021-10-18T11:01:00.114104" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI411" }, { "type": "Combination", "id": "OLI412" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/274/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/274/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP3" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/274/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/274/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/274/?format=api" } }, { "type": "GeneCombination", "id": "275", "attributes": { "gene_relationship": [ "Involved in the same disease", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Immune System" ], "genecomb_metascore": 1, "lastmodified": "2021-10-18T11:01:00.179011" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI413" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/275/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/275/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/275/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/275/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/275/?format=api" } }, { "type": "GeneCombination", "id": "826", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Relevant pathways for phenotype" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:05.632404" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1138" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/826/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/826/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "AMH" }, { "type": "Gene", "id": "MEFV" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/826/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/826/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/826/?format=api" } }, { "type": "GeneCombination", "id": "829", "attributes": { "gene_relationship": [ "Monogenic experiments only" ], "protein_interactions": [], "common_pathways": [], "genecomb_metascore": 0, "lastmodified": "2022-08-04T14:15:05.723889" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1141" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/829/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/829/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "WNT4" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/829/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/829/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/829/?format=api" } }, { "type": "GeneCombination", "id": "1266", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(MEFV, NLRP3)" ], "common_pathways": [ "Immune System" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:26:55.439025" }, "relationships": { "combination_set": { "meta": { "count": 1 }, "data": [ { "type": "Combination", "id": "OLI1788" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1266/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1266/combinations/?format=api" } }, "genes": { "meta": { "count": 4 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP3" }, { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1266/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1266/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1266/?format=api" } }, { "type": "GeneCombination", "id": "1264", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:27:20.737362" }, "relationships": { "combination_set": { "meta": { "count": 2 }, "data": [ { "type": "Combination", "id": "OLI1781" }, { "type": "Combination", "id": "OLI1782" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1264/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1264/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP12" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1264/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1264/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1264/?format=api" } }, { "type": "GeneCombination", "id": "1262", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [ "(MEFV, NLRP3)" ], "common_pathways": [ "NOD-like receptor signaling pathway", "Immune System", "Innate Immune System", "Nucleotide-binding domain", "leucine rich repeat containing receptor (NLR) signaling pathways" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:27:47.292401" }, "relationships": { "combination_set": { "meta": { "count": 4 }, "data": [ { "type": "Combination", "id": "OLI1777" }, { "type": "Combination", "id": "OLI1786" }, { "type": "Combination", "id": "OLI1787" }, { "type": "Combination", "id": "OLI1789" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1262/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1262/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NLRP3" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1262/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1262/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1262/?format=api" } }, { "type": "GeneCombination", "id": "1261", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "Immune System" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:02.772404" }, "relationships": { "combination_set": { "meta": { "count": 3 }, "data": [ { "type": "Combination", "id": "OLI1776" }, { "type": "Combination", "id": "OLI1783" }, { "type": "Combination", "id": "OLI1784" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1261/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1261/combinations/?format=api" } }, "genes": { "meta": { "count": 3 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NOD2" }, { "type": "Gene", "id": "TNFRSF1A" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1261/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1261/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1261/?format=api" } }, { "type": "GeneCombination", "id": "1257", "attributes": { "gene_relationship": [ "Monogenic experiments only", "Involved in the same disease", "Relevant pathways for phenotype", "Same pathway" ], "protein_interactions": [], "common_pathways": [ "NOD-like receptor signaling pathway", "Immune System", "Innate Immune System", "Nucleotide-binding domain", "leucine rich repeat containing receptor (NLR) signaling pathways" ], "genecomb_metascore": 2, "lastmodified": "2024-03-01T14:28:56.289086" }, "relationships": { "combination_set": { "meta": { "count": 10 }, "data": [ { "type": "Combination", "id": "OLI1750" }, { "type": "Combination", "id": "OLI1751" }, { "type": "Combination", "id": "OLI1752" }, { "type": "Combination", "id": "OLI1753" }, { "type": "Combination", "id": "OLI1754" }, { "type": "Combination", "id": "OLI1755" }, { "type": "Combination", "id": "OLI1756" }, { "type": "Combination", "id": "OLI1757" }, { "type": "Combination", "id": "OLI1758" }, { "type": "Combination", "id": "OLI1759" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1257/relationships/combination_set?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1257/combinations/?format=api" } }, "genes": { "meta": { "count": 2 }, "data": [ { "type": "Gene", "id": "MEFV" }, { "type": "Gene", "id": "NOD2" } ], "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1257/relationships/genes?format=api", "related": "https://olida.ibsquare.be/api/genecombinations/1257/genes/?format=api" } } }, "links": { "self": "https://olida.ibsquare.be/api/genecombinations/1257/?format=api" } } ] }